Syngene hiring DMPK In-vitro Bioanalytical Research scientist

Syngene International Limited- Job vacancy for Research Scientist: In-vitro Bioanalytical for DMPK team (Discovery Biology)

We are hiring! If you wish to be part of a dynamic, high-performing team for bringing new solutions to drug discovery and changing people’s lives for the better, please read more. We are looking for Research Scientist: In-vitro Bioanalytical for our DMPK team (Discovery Biology).

Job Title: Research Scientist
Job Location: Bangalore
Job Grade: 7-I

About Syngene: Syngene (www.syngeneintl.com) is an innovation-led contract research, development, and manufacturing organization offering integrated scientific services from early discovery to commercial supply. At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures, and SOPs, in letter and spirit Mandatory expectation for all roles as per Syngene safety guidelines

• Overall adherence to safe practices and procedures of oneself and the teams aligned
• Contributing to the development of procedures, practices, and systems that ensure safe operations and compliance with the company’s integrity & quality standards
• Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
• Ensuring the safety of self, teams, and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensure all assigned mandatory training related to data integrity, health, and safety measures are completed on time by all members of the team including self
• Compliance with Syngene s quality standards at all times

Core Purpose of the Role: Bioanalytical scientist with expertise in handling, and troubleshooting LCMS/MS, LCHRMS/MS, supporting ADME screening assays bioanalysis, MET ID, and understanding of large molecule analysis by LCMS and ability to develop and implement new invitro bioanalytical techniques in line with business needs. The candidate should able to handle a team of 7 to 8 scientists and should act as lab in-charge

Role Accountabilities:

• Delivery of quality data with planning, and execution of bioanalytical activities within the team in agreeable timelines
• Mentor a group of scientists for the development and implementation of high throughput, fit-for-purpose bioanalytical methods to support invitro ADME samples analysis
•  Identification of problems and troubleshooting in quick turn-around time
• Mentoring team members to generate quality data within agreed timelines
• To perform MET ID studies and provide final quality data with interpretation within agreed timelines
• Peptide/ large molecule bioanalysis
• Coordination with related invitro verticals to plan the bioanalysis in cassette
• Excellent written and oral communication skills interacting with internal/external stakeholders
• Operation, maintenance, and troubleshooting of HPLC/ LC-MS/MS system
• Preparation of protocols, reports, and templates for responsible activities
• Instrument maintenance, calibration, and maintaining documentation as per regulatory requirements and company policy
• Adhering to safety and quality policies laid by organization
• Formulation analysis data review and troubleshooting for quicker resolution
• Ensure data compliance as per company procedures
• Coordination with related invitro verticals to plan the bioanalysis in cassette
• Excellent written and oral communication skills interacting with internal/external stakeholders
• Operation, maintenance, and troubleshooting of HPLC/ LC-MS/MS system
• Preparation of protocols, reports, and templates for responsible activities
• Instrument maintenance, calibration, and maintaining documentation as per regulatory requirements and company policy
• Adhering to safety and quality policies laid by organization
• Formulation analysis data review and trouble-shooting for quicker resolution

Leadership Capabilities: Should be able to guide/mentor the juniors for trouble-shooting and BA method development issues. Should be able to lead a team of 7 to 8 scientists and act as lab in-charge.

Syngene Values

All employees will consistently demonstrate alignment with our core values
• Excellence
• Integrity
• Professionalism

Accountabilities as a Syngene Leader (only for Leadership Hires)

• Champion effective Environment, Occupational Health, Safety, and Sustainability (EHSS) practices for the company and oversee compliance with those practices within the Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
• Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
• Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning, and talent retention as a priority.

Specific requirements for this role

Experience: Minimum 12 to 15 years of relevant industrial experience

Demonstrated Capability:

• Expertise in handling & troubleshooting LCMS/MS and LC-HRMS/MS issues
• Interpretation of data for report preparation and communication with the relevant stakeholders and the clients
• Hands-on experience in handling LCMS/MS systems, TOF, and/or Orbitrap
• Expertise in column selection, mobile phase selection, solvent preparations, and sample processing techniques such as protein precipitation, liquid-liquid extraction, and solid phase extraction
• Comprehensive understanding of in vitro ADME assays and technical expertise in troubleshooting the assays. Brief knowledge about Biotransformation of Xenobiotics and basic knowledge of Large molecule analysis using LCMS
• Should be able to deliver the scientific presentation in the departmental journal club and write official Project reports
• Should be equipped with quality policies related to data management and data integrity

Education: M. Pharm in Pharmaceutical sciences/ Relevant master’s degree in pharmaceutical sciences or instrumentation

Skills and Capabilities:

• Good communication skills
• Strong problem-solving and handling skills
• Team Player
• Ability to learn/implement new assays in ADME and Analytical
• Quality compliance skills

Qualifications and Experience: MPharma with 12 to 16 years /Ph.D. with 3 to 5 years.
Looking for experience in invitro Bioanalytical and method development& validation.
Excellent communication and stakeholder management skills are a must.
The candidate should have an excellent understanding of the fundamentals in handling and troubleshooting LCMS/MS, LCHRMS/MS, and supporting ADME screening assays bioanalysis.

Job Location: Bengaluru
Last date to apply: 12 May 2023

APPLICATION PROCESS; Interested candidates may APPLY ONLINE or share their resume with M.Malavika@syngeneintl.com